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                HMG-CoA reductase antibody, 3-羟-3-甲基辅酶A还原酶抗█体

                 
                编 号 PR-1030
                产品名称 HMG-CoA reductase antibody, 3-羟-3-甲基辅酶A还原□ 酶抗体
                规 格 0.2ml
                价 格 1980元
                应 用 IHC,WB,ELISA,ICC,IP,IF
                品 牌 Hopebiot

                详细信息: 说明书◤下载

                Background:  HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis.

                Description: Rabbit polyclonal to HMG-CoA reductase

                Immunogen: KLH conjugated synthetic peptide derived from HMG-CoA reductase

                Specificity:  ·Reacts with Human, Mouse, Rabbit, Cow, Pig, Dog and Rat.

                ·Isotype: IgG

                Application:  ·Western blotting: 1/200-500. Predicted Mol wt: 97 kDa;

                ·Immunohistochemistry (Frozen/paraffin tissue section): 1/100-200;

                ·Immunocytochemistry: 1/100;

                ·ELISA: 1/500;

                ·Optimal working dilutions must be determined by the end user.

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